Osteoclasts : Morphology, Functions & Clinical Implications
Book Details
Format
Hardback or Cased Book
ISBN-10
1620813068
ISBN-13
9781620813065
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Oct 19th, 2012
Print length
169 Pages
Weight
502 grams
Dimensions
26.10 x 18.40 x 1.50 cms
Product Classification:
Musculoskeletal medicine
Ksh 36,000.00
Not available
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Quality
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Osteoclasts are highly specialised cells, derived from the hematopoietic lineage, that resorb mineralised bone matrix. Osteoclast precursors can be recruited to the bone remodelling sites by specific cytokines in the microcellular environment, including some secreted by osteoblasts, fibroblasts, and osteocytes. In this book, the authors present current research in the study of the morphology, functions and clinical implications of osteoclasts. Topics include osteoclast formation and function and its risk in skeletal bone disease; the high osteoclastogenic potential of human osteosarcoma cells; osteoclast biology regarding Paget''s disease and p62 mutations; the role of immuno-skeletal interface in the regulation of osteoclast formation; and osteoclasts in patients with neurofibromatosis 1.
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