Osteoclasts : Morphology, Functions & Clinical Implications

Name: Osteoclasts
Brand: Nova Science Publishers Inc
SKU: 9781620813065
Price: 36000 KES
Availability: OutOfStock
ISBN: 9781620813065

by Alexander J Brown

Book Details

Format Hardback

ISBN-10 1620813068

ISBN-13 9781620813065

Publisher Nova Science Publishers Inc

Imprint Nova Science Publishers Inc

Country of Manufacture US

Country of Publication GB

Publication Date Oct 19th, 2012

Print length 169 Pages

Weight 502 grams

Dimensions 26.10 x 18.40 x 1.50 cms

Product Classification: Musculoskeletal medicine

KSh 36,000.00

Not available 0 in stock

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Osteoclasts are highly specialised cells, derived from the hematopoietic lineage, that resorb mineralised bone matrix. Osteoclast precursors can be recruited to the bone remodelling sites by specific cytokines in the microcellular environment, including some secreted by osteoblasts, fibroblasts, and osteocytes. In this book, the authors present current research in the study of the morphology, functions and clinical implications of osteoclasts. Topics include osteoclast formation and function and its risk in skeletal bone disease; the high osteoclastogenic potential of human osteosarcoma cells; osteoclast biology regarding Paget''s disease and p62 mutations; the role of immuno-skeletal interface in the regulation of osteoclast formation; and osteoclasts in patients with neurofibromatosis 1.

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