Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC
Book Details
Format
Hardback or Cased Book
Book Series
Cancer Sensitizing Agents for Chemotherapy
ISBN-10
0128228334
ISBN-13
9780128228333
Publisher
Elsevier Science Publishing Co Inc
Imprint
Academic Press Inc
Country of Manufacture
NL
Country of Publication
GB
Publication Date
Feb 1st, 2023
Print length
150 Pages
Weight
474 grams
Dimensions
24.30 x 20.10 x 1.40 cms
Product Classification:
Life sciences: general issues
Ksh 24,650.00
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Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer.
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