From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas.
Table of Contents: Preface. Importance of the subject in the context of type I diabetes (2-3 pages) The pancreas (15 pages) Pancreatic development (50-60 pages) Pancreatic regeneration (30-40 pages) Models of regeneration Stem cells vs. beta cell replication Stem cell differentiation: general approaches (20-30 pages) Recapitulation of pancreatic development Signal-driven strategies Gene transfer and protein transduction Physiological variables Embryonic stem cells and pancreatic differentiation (40 pages) Adult stem cells and pancreatic differentiation (60 pages) Bone marrow Umbilical cord Ductal and acinar cells Mesenchymal stem cells and de-differentiation Transdifferentiation (30 pages) Remaining challenges and clinical perspectives (20-30 pages)
Get Pancreatic Stem Cells by Juan Domínguez-Bendala at the best price and quality guaranteed only at Werezi Africa's largest book ecommerce store. The book was published by Humana Press Inc. and it has 154 pages.
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