Pancreatic Stem Cells
Book Details
Format
Paperback / Softback
Book Series
Stem Cell Biology and Regenerative Medicine
ISBN-10
1617794864
ISBN-13
9781617794865
Publisher
Humana Press Inc.
Imprint
Humana Press Inc.
Country of Manufacture
US
Country of Publication
GB
Publication Date
Dec 2nd, 2011
Print length
154 Pages
Ksh 18,000.00
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From the discovery of Pdx1, the first “master gene” of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas.
Table of Contents: Preface. Importance of the subject in the context of type I diabetes (2-3 pages) The pancreas (15 pages) Pancreatic development (50-60 pages) Pancreatic regeneration (30-40 pages) Models of regeneration Stem cells vs. beta cell replication Stem cell differentiation: general approaches (20-30 pages) Recapitulation of pancreatic development Signal-driven strategies Gene transfer and protein transduction Physiological variables Embryonic stem cells and pancreatic differentiation (40 pages) Adult stem cells and pancreatic differentiation (60 pages) Bone marrow Umbilical cord Ductal and acinar cells Mesenchymal stem cells and de-differentiation Transdifferentiation (30 pages) Remaining challenges and clinical perspectives (20-30 pages)
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