Pharmaceutical Powder Compaction Technology

Pharmaceutical Powder Compaction Technology

"Revised to reflect modern pharmaceutical compacting techniques, this Second Edition guides pharmaceutical engineers, formulation scientists, and product development and quality assurance personnel through the compaction formulation process and application. Compaction of powder constituents both active ingredient and excipients is examined to ensure consistent and reproducible disintegration and dispersion profiles. This unique reference covers: the physical structure of pharmaceutical compacts bonding phenomena that occur during powder compaction compression mechanisms of pharmaceutical particles theories and basic principles of powder compaction New topics include: compaction data analysis techniques the migration of powder constituents into commercialmanufacture instrumentation for compaction compaction functionality testing, which is likely to become a USP requirement design space for compaction metrics required for scalability in tablet compression interactive compaction and preformulation databasefor commonly used excipients"--Provided by publisher.