Polyploidization and Cancer
Softcover reprint of the original 1st ed. 2010
Book Details
Format
Paperback / Softback
Book Series
Advances in Experimental Medicine and Biology
ISBN-10
1493951432
ISBN-13
9781493951437
Edition
Softcover reprint of the original 1st ed. 2010
Publisher
Springer-Verlag New York Inc.
Imprint
Springer-Verlag New York Inc.
Country of Manufacture
US
Country of Publication
GB
Publication Date
Aug 23rd, 2016
Print length
151 Pages
Weight
334 grams
Dimensions
25.20 x 17.70 x 1.20 cms
Product Classification:
Medical research
Ksh 23,400.00
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Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation.
Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overviewsubjects relating to polyploidization and cancer.
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