Progress in Medicinal Chemistry
Book Details
Format
Hardback or Cased Book
Book Series
Progress in Medicinal Chemistry
ISBN-10
0444511431
ISBN-13
9780444511430
Publisher
Elsevier Science & Technology
Imprint
Elsevier Science Ltd
Country of Manufacture
US
Country of Publication
GB
Publication Date
Apr 15th, 2004
Print length
450 Pages
Weight
690 grams
Product Classification:
Pharmaceutical technology
Ksh 22,500.00
Manufactured on Demand
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This volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis; and a survey of semi-synthetic and totally synthetic antibiotics and anti-HIV agents and their sites of interaction; the development of inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) for the treatment of hypercholesterolemia; a description of recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action; and information on inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), (required for vital replication) as one of the most attractive targets for HCV infections.
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