Protein Degradation in Health and Disease
Book Details
Format
Hardback or Cased Book
ISBN-10
3540425942
ISBN-13
9783540425946
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Jan 1st, 2002
Print length
140 Pages
Product Classification:
MetabolismOncologyBiochemistryCellular biology (cytology)
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This work describes how aged proteins are eliminated during cell metabolism, how cell proliferation is regulated by protein degradation and how its deregulation can contribute to the development of cancer. Attempts aimed at correcting these pathologies are also treated.
Roles of SCF and VHL Ubiquitin Ligases in Regulation of Cell Growth.- Aging of Proteins and the Proteasome.- Protein Degradation in the Aging Organism.- Protein Degradation in Alzheimer''s Disease and Aging of the Brain.- Protein Degradation in Human Disease.- The 26S Proteasome.- Proteasome Inhibitors.
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