Protein Degradation with New Chemical Modalities : Successful Strategies in Drug Discovery and Chemical Biology
Book Details
Format
Hardback or Cased Book
Book Series
Drug Discovery Series
ISBN-10
1788016866
ISBN-13
9781788016865
Publisher
Royal Society of Chemistry
Imprint
Royal Society of Chemistry
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Oct 8th, 2020
Print length
358 Pages
Weight
730 grams
Dimensions
16.20 x 23.90 x 3.00 cms
Product Classification:
PharmacologyPharmacologyBiochemistryProteinsEnzymology
Ksh 32,200.00
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This book provides a comprehensive overview from the leading academic and industrial experts on recent developments, scope and limitations in this dynamically growing research area; an ideal reference work for researchers in drug discovery and chemical biology as well as advanced students.
Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research. In particular, the development of proteolysis targeting chimera (PROTACs) as potential drugs capable of recruiting target proteins to the cellular quality control machinery for elimination has opened new avenues to address traditionally ‘difficult to target’ proteins. This book provides a comprehensive overview from the leading academic and industrial experts on recent developments, scope and limitations in this dynamically growing research area; an ideal reference work for researchers in drug discovery and chemical biology as well as advanced students.
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