Protein Misfolding
Book Details
Format
Hardback or Cased Book
ISBN-10
160456881X
ISBN-13
9781604568813
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Oct 1st, 2008
Print length
234 Pages
Weight
682 grams
Dimensions
26.10 x 18.80 x 1.90 cms
Product Classification:
Biochemistry
Ksh 36,000.00
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Proteins occasionally exhibit the potential to adopt alternate folds under natural or artificial conditions. These conformational changes can lead to the creation of disease-forming amyloid plaques or accumulation of insoluble aggregates in over-expressed recombinant proteins. Because alternate folds challenge the traditional notion of structurally defined proteins and frequently lead to problems in natural and laboratory settings, it is tempting to characterise structurally ambiguous proteins as ill-behaved. Unfortunately, this perspective masks the positive role structural ambiguity can play in protein function and evolution. This book provides leading-edge research on the study of protein misfolding from researchers all over the globe.
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