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Radiotracers in Drug Development
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Radiotracers in Drug Development

Book Details

Format Hardback or Cased Book
ISBN-10 0849333474
ISBN-13 9780849333477
Publisher Taylor & Francis Inc
Imprint CRC Press Inc
Country of Manufacture US
Country of Publication GB
Publication Date Apr 3rd, 2006
Print length 320 Pages
Weight 589 grams
Ksh 49,500.00
Re-Printing 0 in stock

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A unique reference and training aid that meets the essential needs of every drug metabolism department or drug metabolism research team, this book provides insight into the use and practice of ADME in a way that is both instructive and practical. Moving across biology, chemistry, and physics, this interdisciplinary resource explains how to employ r
Although there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drug’s absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the basics of scintillation counting and untangling the various data processing methods often specific to individual manufacturers.

The chapters include descriptions of the latest micro-plate counters and the growing applications of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. In addition to describing how the analytical technologies work, the contributors explain how the data are interpreted and used in the drug registration process.

A unique reference and training aid essential for every drug metabolism department or drug metabolism research team, the book provides insight into the use and practice of ADME in a way that is both instructive and practical. Moving easily across the boundaries of biology, chemistry, and physics, this is the only comprehensive, interdisciplinary resource covering the how-tos of employing radiotracers in drug development. It provides detailed information on how the science is relevant to the registration process.


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