Rapid Cell Magnetisation Using Cationised Magnetoferritin
Softcover reprint of the original 1st ed. 2017
Book Details
Format
Paperback / Softback
Book Series
Springer Theses
ISBN-10
3319868381
ISBN-13
9783319868387
Edition
Softcover reprint of the original 1st ed. 2017
Publisher
Springer International Publishing AG
Imprint
Springer International Publishing AG
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Aug 4th, 2018
Print length
166 Pages
Ksh 16,200.00
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Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope.
Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.
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