Regulation of Vitamin A Homeostasis by the Stellate Cell (Vitamin A-Storing Cell) System
Book Details
Format
Paperback / Softback
ISBN-10
1617613134
ISBN-13
9781617613135
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Feb 16th, 2011
Print length
55 Pages
Weight
106 grams
Dimensions
21.60 x 13.90 x 0.50 cms
Product Classification:
Dietetics & nutrition
Ksh 9,550.00
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Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis. In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesise a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins. Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts. This book discusses and presents research on vitamin A-storing cells.
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