Resistance to Molecular Therapies for Hepatocellular Carcinoma
Softcover reprint of the original 1st ed. 2017
Book Details
Format
Paperback / Softback
Book Series
Resistance to Targeted Anti-Cancer Therapeutics
ISBN-10
3319858505
ISBN-13
9783319858500
Edition
Softcover reprint of the original 1st ed. 2017
Publisher
Springer International Publishing AG
Imprint
Springer International Publishing AG
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Aug 2nd, 2018
Print length
147 Pages
Product Classification:
Oncology
Ksh 23,400.00
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This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance;
This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.
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