Senotherapeutics : From Cellular Senescence to Disease Management

This book provides a comprehensive overview of the emerging field of senotherapeutics and its potential applications in various diseases.

This book provides a comprehensive overview of the emerging field of senotherapeutics and its potential applications in various diseases. The initial chapter elucidates the central role of cellular senescence and the senescence-associated secretory phenotype (SASP) in the intricate balance between health and disease. The subsequent chapter examines the origin of senotherapeutics, introducing the concepts of senolytics and senomorphics for combating senescence and its associated disorders. The book also focuses on the potential of senotherapeutics in managing neurological disorders and neurodegenerative diseases. Furthermore, it investigates the intersection of senotherapeutics with cancer therapy, shedding light on innovative treatments and their role against cancer. It also discusses the broader role of senotherapeutics in aging and its associated disorders such as osteoporosis and osteoarthritis, offering insights into their implications for geriatric medicine. The book reviews the novel application of senotherapeutics in skincare and dermatological diseases, as well as metabolic disorders. This book is intended for researchers in the fields of biomedicine, pharmacology, and gerontology, as well as healthcare professionals. Key FeaturesOffers a comprehensive exploration of senotherapeutics, spanning various diseases and conditions, providing a holistic understanding of its potential applications. Provides a conceptual framework for cellular senescence and the senescence-associated secretory phenotype (SASP) and their relevance to health and disease. Examines the potential of senotherapeutics in addressing neurological disorders, neurodegenerative diseases, and cancer therapy. Explores the broader role of senotherapeutics in the context of aging and associated disorders such as osteoarthritis and osteoporosis. Reviews the application of senotherapeutics in skincare and dermatological concerns, as well as metabolic disorders.