Simulation for Designing Clinical Trials : A Pharmacokinetic-Pharmacodynamic Modeling Perspective
Book Details
Format
Paperback / Softback
ISBN-10
0367395606
ISBN-13
9780367395605
Publisher
Taylor & Francis Ltd
Imprint
CRC Press
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Sep 19th, 2019
Print length
424 Pages
Weight
453 grams
Ksh 12,800.00
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Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects'' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.
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