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Simulation for Designing Clinical Trials
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Simulation for Designing Clinical Trials : A Pharmacokinetic-Pharmacodynamic Modeling Perspective

Book Details

Format Hardback or Cased Book
ISBN-10 0824708628
ISBN-13 9780824708627
Publisher Taylor & Francis Inc
Imprint CRC Press Inc
Country of Manufacture GB
Country of Publication GB
Publication Date Dec 12th, 2002
Print length 424 Pages
Weight 716 grams
Dimensions 23.80 x 15.90 x 2.90 cms
Ksh 34,200.00
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Supplying a framework for employing simulation as an experiment, this book discusses how to clinically trial designs according to their probability for success. It gives techniques to define distributions of virtual subjects' characteristics, and methods to determine the sensitivity of the trial design.
Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects'' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.

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