Supercritical Fluid Chromatography and Extraction

Supercritical Fluid Chromatography and Extraction, Second Edition presents an in-depth look at the modern practices of supercritical fluid chromatography (SFC) and extraction (SFE). The book emphasizes how both techniques can be implemented effectively in laboratory science for the analysis, isolation, and production of compounds. With significant advancements in instrumentation, SFC has gained renewed interest and enhanced its reputation within the scientific community, offering new possibilities beyond column liquid chromatography. SFE has been predominantly used in the food industry but is now expanding into various other fields with diverse applications. This book serves as a valuable resource for chemical engineers, chemists, researchers, academics, and students. It provides essential knowledge for those working with supercritical fluids at both preparative and process-scale applications. Additionally, it is ideal for individuals looking to enter the fields of SFC and SFE, offering a comprehensive introduction that consolidates their understanding and enhances their skills. It covers advancements, benefits, and potential applications of both techniques, ensuring readers are well-equipped to leverage these methods in their work.

Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Recent, significant improvements in instrumentation have rekindled interest in SFC and have enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its potential beyond traditional liquid chromatography, yet many of its capabilities remain underappreciated. Supercritical Fluid Chromatography and Extraction explores contemporary supercritical fluid chromatography and extraction and how it should be implemented in laboratory science for analysis, isolation, and production. New to This EditionThis new edition details recent advances and applications of supercritical fluids in sample prep, instrumental analysis, and process-scale, including SFE, making it a comprehensive resource for both techniques. Further enhancements to this edition include:Expanded section on SFC theory to include gradient elutionA new chapter on general detectors for SFCEnhanced method development coverage, with focus on gradient elution practicesIncludes multidimensional SFC, SFC × SFC, and LC-SFCFeatures comprehensive information on accelerated solvents, comparing solvent and extraction techniques. Highlights environmental monitoring and analysis applications of SFE. Widely used in the food industry for decades, SFE is now expanding into new fields. Supercritical Fluid Chromatography and Extraction, Second Edition serves as a valuable resource for chemical engineers, chemists, researchers, students, and academics working with supercritical fluids at preparative and process scales. It’s also an ideal introduction for newcomers to SFC and SFE.

Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Recent, significant improvements in instrumentation have rekindled interest in SFC and have enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its potential beyond traditional liquid chromatography, yet many of its capabilities remain underappreciated. Supercritical Fluid Chromatography and Extraction explores contemporary supercritical fluid chromatography and extraction and how it should be implemented in laboratory science for analysis, isolation, and production.

New to This Edition
This new edition details recent advances and applications of supercritical fluids in sample prep, instrumental analysis, and process-scale, including SFE, making it a comprehensive resource for both techniques. Further enhancements to this edition include:

• Expanded section on SFC theory to include gradient elution
• A new chapter on general detectors for SFC
• Enhanced method development coverage, with focus on gradient elution practices
• Includes multidimensional SFC, SFC × SFC, and LC-SFC
• Features comprehensive information on accelerated solvents, comparing solvent and extraction techniques.
• Highlights environmental monitoring and analysis applications of SFE.

Widely used in the food industry for decades, SFE is now expanding into new fields. Supercritical Fluid Chromatography and Extraction, Second Edition serves as a valuable resource for chemical engineers, chemists, researchers, students, and academics working with supercritical fluids at preparative and process scales. It’s also an ideal introduction for newcomers to SFC and SFE.