Targeting Protein-Protein Interactions by Small Molecules
Softcover Reprint of the Original 1st 2018 ed.
Book Details
Format
Paperback / Softback
ISBN-10
9811344965
ISBN-13
9789811344961
Edition
Softcover Reprint of the Original 1st 2018 ed.
Publisher
Springer Verlag, Singapore
Imprint
Springer Verlag, Singapore
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Dec 23rd, 2018
Print length
329 Pages
Product Classification:
Pre-clinical medicine: basic sciencesChemistryOrganic chemistryBiochemistry
Ksh 16,200.00
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This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development.
This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.
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