The Biology of Oligodendrocytes
Book Details
Format
Hardback or Cased Book
ISBN-10
0521899656
ISBN-13
9780521899659
Publisher
Cambridge University Press
Imprint
Cambridge University Press
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Oct 21st, 2010
Print length
304 Pages
Weight
612 grams
Dimensions
16.00 x 23.30 x 1.90 cms
Product Classification:
Neurology & clinical neurophysiology
Ksh 22,850.00
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This is the first dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics and immunobiology. Later chapters explore the role that damage to these often overlooked cells plays in diseases of the central nervous system, with a particular focus on multiple sclerosis.
Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.
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