The Politics of Personalised Medicine : Pharmacogenetics in the Clinic

Applies a social science perspective to exploring issues arising in clinical practice as a result of drug development linked to genetic testing. These include the social context within which new drugs are trialled, attitudes of the clinicians asked to administer them, expectations of clinicians and patients and associated ethical issues.

Pharmacogenetics, the use of genetic testing to prescribe and develop drugs, has been hailed as a revolutionary development for the pharmaceutical industry and modern medicine. Supporters of ''personalised medicine'' claim the result will be safer, cheaper, more effective drugs, and their arguments are beginning to influence policy debates. Based on interviews with clinicians, researchers, regulators and company representatives, this book explores the impact of pharmacogenetics on clinical practice, following two cases of personalised medicine as they make their way from the laboratory to the clinic. It highlights the significant differences between the views of supporters of pharmacogenetics in industry and those who use the technology at the clinical ''coal face''. Theoretically, this work builds on the developing area of the sociology of socio-technical expectations, highlighting the way in which promoters of new technologies build expectations around it, through citation and the creation of technological visions.