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The Post-Imperative Negative Variation in Schizophrenic Patients and Healthy Subjects
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The Post-Imperative Negative Variation in Schizophrenic Patients and Healthy Subjects

Book Details

Format Paperback / Softback
ISBN-10 3631310781
ISBN-13 9783631310786
Publisher Peter Lang GmbH
Imprint Peter Lang GmbH
Country of Manufacture GB
Country of Publication GB
Publication Date Dec 1st, 1996
Print length 386 Pages
Weight 486 grams
Dimensions 15.00 x 21.00 x 2.00 cms
Product Classification: PsychiatryPsychiatry
Ksh 11,300.00
Manufactured on Demand 0 in stock

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The Post-Imperative Negative Variation (PINV) is an event-related brain potential that has scarcely been investigated experimentally in schizophrenic patients. Four consecutive experiments using a visual delayed matching-to-sample task show that the PINV (1) is sensitive to the ambiguity in the matching process both in schizophrenic patients and healthy subjects, (2) is sensitive to the provisional memory load in schizophrenic patients only, (3) is related to the experimentally induced motor response, and (4) has a frontolateral topography that distinguishes schizophrenic patients and schizotypal subjects from healthy controls. Taken together, these results suggest that the prefrontal cortex or those cerebral structures functionally linked with it contribute to the rising of the PINV in schizophrenic patients.

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