Therapeutic Immunosuppression

Designed to provide the theory behind various approaches, this work has broad applications, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma.

1. Calcineurin-targeted inhibition of immune reactivity; L. Kung, P.F. Halloran. 2. Experimental immunosuppressive agents; J. Klupp, R. Morris. 3. Polyclonal and monoclonal antibodies; L. Chatenoud. 4. Cytokines and their receptors as therapeutic targets; P. Nickerson. 5. Novel strategies using MHC peptides; C.C. Magee, M.H. Sayegh. 6. Costimulatory blockade as a therapeutic regimen for prolonging allograft survival and inducing tolerance: an overview of recent research; M.M. Hamawy, et al. 7. Oral tolerance; H.L. Weiner. 8. Hematopoietic stem cell chimerism and tolerance induction; H. Shirwan, S.T. Ildstad. 9. Strategies to promote tolerance induction using dendritic cells; A.W. Thomson, L. Lu. 10. Gene therapy for autoimmune disease and transplantation; C.H. Evans, et al. 11. Local immunosuppression: the eye; J.W. Streilein, A.W. Taylor. 12. Topical skin immune system response modifiers; J.D. Bos. 13. Local immunosuppression: the lung; A.T. Iacono, et al. 14. Therapy of autoimmune connective tissue diseases; T.M. Wright, D.P. Ascherman. 15. Immunotherapy for allergic diseases; D. Umetsu, R.H. DeKruyff. 16. Therapeutic strategies for xenotransplantation; J.L. Platt. 17. Medical complications of immunosuppression; J. McCauley, R. Shapiro. 18. Neurological complications of immunosuppression; B.H. Eidelman, R. Shapiro. 19. Infectious complications of immunosuppression; S. Kusne, R. Shapiro. Index.