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Therapeutic Strategies to Overcome ALK Resistance in Cancer
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Therapeutic Strategies to Overcome ALK Resistance in Cancer

Book Details

Format Hardback or Cased Book
ISBN-10 012821774X
ISBN-13 9780128217740
Publisher Elsevier Science Publishing Co Inc
Imprint Academic Press Inc
Country of Manufacture NL
Country of Publication GB
Publication Date Jan 14th, 2021
Print length 216 Pages
Weight 590 grams
Dimensions 24.20 x 26.60 x 1.80 cms
Product Classification: OncologyRespiratory medicine
Ksh 24,300.00
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Therapeutic Strategies to Overcome ALK Resistance in Cancer, Volume 13, presents current strategies to improve and prolong clinical benefit in ALK driven cancers. Most patients with ALK-driven cancer are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance invariably develops. This book discusses topics such as structure and function of ALK, ALK rearranged lung cancer, resistance mechanisms to ALK TKI tumors, and novel therapeutic strategies to enhance crizotinib anti-tumor efficacy in ALCL. Additionally, it encompasses information on drug combinations to enhance ALK TKI anti-tumor efficacy in neuroblastoma and future perspectives in the field. This book is a valuable resource for cancer researchers, clinicians and several members of biomedical field who need to understand more about how to fight ALK resistance in cancer treatment.

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