Transcription Factors and Human Disease
Book Details
Format
Hardback or Cased Book
Book Series
Oxford Monographs on Medical Genetics
ISBN-10
0195112393
ISBN-13
9780195112399
Publisher
Oxford University Press Inc
Imprint
Oxford University Press Inc
Country of Manufacture
GB
Country of Publication
GB
Publication Date
Oct 29th, 1998
Print length
384 Pages
Weight
907 grams
Dimensions
23.90 x 15.70 x 3.10 cms
Ksh 12,000.00
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This work discusses the basic science of transcriptional regulation, and describes inherited human diseases attributable to mutations in DNA sequences encoding transcription factors or their cognate binding sites.
Transcription factors are essential mediators of the genetic programs that control development and physiology. This exciting book presents current knowledge of transcription factors from two viewpoints. First, the basic science of transcriptional regulation is discussed. Second, inherited human diseases attributable to mutations in DNA sequences encoding transcription factors or their cognate binding sites are described. Readers are also introduced to the involvement of transcription factors in somatic cell genetic disease (cancer) and epigenetic disease (teratogenesis).
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