Transplantation and Changing Management of Organ Failure

This text addresses issues in the management of organ failure, whether humans will remain the only source for organ procurement, prospects for engineering in organ replacement, and whether transplantation will remain the most appropriate approach to organ failure.

Past and Future Alternatives and Strategies. Trends in the epidemiology of end-stage renal disease over the last decade; P. Landais. Answers to liver graft shortage: hepatocyte transplantation and bioartificial liver; Y. Calmus. Enzymatic and biochemical substitutes to organ transplantation in inborn errors of metabolism; P. Cochat. Tolerance induction; K.J. Wood. Xenotransplantation: immunological advances; G. Blancho. Liver Replacement Therapy. Living donor in liver transplantation as novel graft source; O. Boillot. Ex-situ liver support; I. Méchet. Renal Replacement Therapy. Preventing end-stage renal disease: fact or fiction? B. Kasiske. Transplantation and short daily hemodialysis; J. Traeger. Comparison of survival probabilities between renal transplant recipients and patients undergoing regular dialysis: a single center prospective study; G. Segoloni. Transplantation versus dialysis in aged and type 2 diabetic patients; C. Pouteil-Noble. Pancreas Replacement Therapy. External and implantable insulin pumps: current place in the treatment of diabetes; J.L. Selam. Pancreas and islet transplantation in the treatment of type 1 diabetes; X. Martin. Perspectives in early detection and management of IDDM; C. Thivolet. Heart and Lung Replacement Therapy. Mechanical circulatory support: today''s fact and future horizons; A. El-Banayosys. Intra-myocardial myoblast injection; P. Ménasché. Ambulatory management of primary pulmonary hypertension; J.L. Vachiéry. Cystic fibrosis: conservative management; A. Clément. Emerging Transplantations and Management. Intestinal transplantation; O. Goulet. Intracerebralgrafting of fetal neuroblasts for neurodegenerative diseases: experimental bases and clinical results; M. Pechansky. Skin equivalents; O. Damour. Concluding Remarks. Public health issues from European countries; M. Manyalich. Clinical evaluation of organ transplantation in France; Y. Matillon. From Lyon to Louisville: the need for tolerance; L. Ross.