Tumor Necrosis Factor : Structure, Enzyme Regulation & Role in Health & Disease
Book Details
Format
Paperback / Softback
ISBN-10
1624177212
ISBN-13
9781624177217
Publisher
Nova Science Publishers Inc
Imprint
Nova Science Publishers Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Jun 19th, 2013
Print length
110 Pages
Weight
232 grams
Dimensions
22.80 x 15.40 x 0.80 cms
Product Classification:
Immunology
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Tumor necrosis factor-alpha (TNF-a) is a potent pro-inflammatory cytokine exerting pleiotropic effects on various cell types and plays a critical role in the pathogenesis of chronic inflammatory diseases. In this book, the authors discuss the structure, enzyme regulation and role in health and disease of TNF. Topics include TNF-a related to signal pathways and neuronal diseases; the role of TNF-a in rheumatoid arthritis and autoimmunity; the presence of 308-A TNF allele and its association with the clinical parameters of myelodysplastic syndromes; the significance of TNF in the immune response against tuberculosis; and TNF-a signaling and cathespin B.
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