Ubiquitin-proteasome Proteolytic System, The: From Classical Biochemistry To Human Diseases
Book Details
Format
Hardback or Cased Book
Book Series
Recent Advances In Human Biology
ISBN-10
9812381007
ISBN-13
9789812381002
Publisher
World Scientific Publishing Co Pte Ltd
Imprint
World Scientific Publishing Co Pte Ltd
Country of Manufacture
SG
Country of Publication
GB
Publication Date
Nov 19th, 2002
Print length
240 Pages
Weight
496 grams
Dimensions
23.50 x 16.50 x 1.50 cms
Product Classification:
PhysiologyProteinsHuman biology
Ksh 14,200.00
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Ubiquitin-proteosome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes. This text tells the story of the ubiquitin system as we know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, and more.
Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory.This book tells the story of the ubiquitin system as we currently know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes.
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