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Germfree and Gnotobiotic Animal Models : Background and Applications

By: (Author) Bernard S. Wostmann

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Ksh 20,700.00

Format: Hardback or Cased Book

ISBN-10: 084934008X

ISBN-13: 9780849340086

Publisher: Taylor & Francis Inc

Imprint: CRC Press Inc

Country of Manufacture: US

Country of Publication: GB

Publication Date: Jun 19th, 1996

Print length: 202 Pages

Weight: 430 grams

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The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. This work explores practical applications such as the role of microorganisms in dental caries, cholesterol metabolism, cancer, and Chagas' disease and other parasitic diseases.
The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.

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