Germfree and Gnotobiotic Animal Models : Background and Applications
Book Details
Format
Hardback or Cased Book
ISBN-10
084934008X
ISBN-13
9780849340086
Publisher
Taylor & Francis Inc
Imprint
CRC Press Inc
Country of Manufacture
US
Country of Publication
GB
Publication Date
Jun 19th, 1996
Print length
202 Pages
Weight
430 grams
Product Classification:
Medical researchVeterinary medicine: laboratory animalsMicrobiology (non-medical)
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The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. This work explores practical applications such as the role of microorganisms in dental caries, cholesterol metabolism, cancer, and Chagas' disease and other parasitic diseases.
The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.
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