Hypopigmentation

There are many disorders of a lack of pigmentation in the skin, with different causations

and effects, of which vitiligo is only the best known; this comprehensive text from international

experts will enable clinicians to diagnose the full range of these conditions and suggest

the most effective management options for their patients.

Basic concepts of melanocyte biology * Approach to hypopigmentation *

Historical review of vitiligo * Epidemiology and classification of vitiligo * Pathophysiology

of vitiligo * Segmental vitiligo * Childhood versus post-childhood vitiligo * Pharmacological

therapy of vitiligo * Surgical treatment of vitiligo * Phototherapy and lasers in the treatment

of vitiligo * Emerging treatments for vitiligo * Tuberous sclerosis complex * Oculocutaneous

albinism * Hermansky-Pudlak syndrome, Chediak-Chigasi syndrome, and Griscelli

syndrome * Piebaldism * Waardenburg syndrome * Alezzandrini syndrome, Margolis

syndrome, Cross syndrome, and other rare genetic disorders * Mosaic hypopigmentation

* Skin disorders causing post-inflammatory hypopigmentation * Infectious and parasitic

causes of hypopigmentation * Melanoma leukoderma * Halo nevi * Drug-induced hypopigmentation

* Hypopigmentation from chemical and physical agents * Guttate hypomelanosis

and progressive hypomelanosis of the trunk (progressive macular hypomelanosis)